IL-33 and its decoy sST2 in patients with Alzheimer’s disease and mild cognitive impairment

@article{Saresella2020IL33AI,
  title={IL-33 and its decoy sST2 in patients with Alzheimer’s disease and mild cognitive impairment},
  author={M. Saresella and I. Marventano and F. Piancone and Francesca La Rosa and Daniela Galimberti and C. Fenoglio and E. Scarpini and M. Clerici},
  journal={Journal of Neuroinflammation},
  year={2020},
  volume={17}
}
  • M. Saresella, I. Marventano, +5 authors M. Clerici
  • Published 2020
  • Biology, Medicine
  • Journal of Neuroinflammation
  • Background Interleukin-33 is a cytokine endowed with pro- and anti-inflammatory properties that plays a still poorly defined role in the pathogenesis of a number of central nervous system (CNS) conditions including Alzheimer’s disease (AD). We analyzed this cytokine and its decoy receptor sST2 in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Method IL-33 and sST2 were analyzed in serum and CSF of AD and MCI patients, comparing the results to those obtained in age-matched healthy… CONTINUE READING

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