IL-33: a novel danger signal system in atopic dermatitis.

  title={IL-33: a novel danger signal system in atopic dermatitis.},
  author={Ferda Cevikbas and Martin S Steinhoff},
  journal={The Journal of investigative dermatology},
  volume={132 5},
IL-33 is a newly recognized cytokine of the IL-1 cytokine family that has recently been attributed to the epithelial "alarmin" defense system. IL-33 is released by the epithelial cells in various tissues and organs, including keratinocytes, endothelial cells, and immune cells. Recent reports have suggested that IL-33 might be a critical part of the innate immunity, although its precise role is as yet poorly understood. In several organs, IL-33 appears to drive T helper type 2 (Th2) responses… CONTINUE READING
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Publications referenced by this paper.
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CONFLICT OF INTEREST The author states no conflict of interest

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