IL-32 up-regulation is associated with inflammatory cytokine production in allergic rhinitis.

@article{Jeong2011IL32UI,
  title={IL-32 up-regulation is associated with inflammatory cytokine production in allergic rhinitis.},
  author={Hyun-Ja Jeong and S. Shin and Hyun-A Oh and Min-Ho Kim and Joong-Saeng Cho and Hyung-Min Kim},
  journal={The Journal of pathology},
  year={2011},
  volume={224 4},
  pages={553-63}
}
IL-32 is a described pro-inflammatory cytokine produced by T lymphocytes, natural killer cells, monocytes, and epithelial cells. However, the specific mechanism of IL-32 on allergic rhinitis (AR) has not been elucidated. Here, we report a significant increase of IL-32 protein and mRNA in the nasal mucosa of AR patients. In addition, in nasal mucosa tissue from AR patients, the level of IL-32 production correlated with inflammation, IL-1β, IL-18, and granulocyte-macrophage colony-stimulating… CONTINUE READING

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