IL-23 promotes tumour incidence and growth

@article{Langowski2006IL23PT,
  title={IL-23 promotes tumour incidence and growth},
  author={John L. Langowski and Xueqing Zhang and L. Wu and Jeanine D. Mattson and Taiying Chen and K. Smith and B. Basham and T. Mcclanahan and R. Kastelein and M. Oft},
  journal={Nature},
  year={2006},
  volume={442},
  pages={461-465}
}
  • John L. Langowski, Xueqing Zhang, +7 authors M. Oft
  • Published 2006
  • Biology, Medicine
  • Nature
  • Chronic inflammation has long been associated with increased incidence of malignancy and similarities in the regulatory mechanisms have been suggested for more than a century. Infiltration of innate immune cells, elevated activities of matrix metalloproteases and increased angiogenesis and vasculature density are a few examples of the similarities between chronic and tumour-associated inflammation. Conversely, the elimination of early malignant lesions by immune surveillance, which relies on… CONTINUE READING
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