IL-2 production by intestinal lamina propria cells in normal inflamed and cancer-bearing colons.

@article{Pullman1992IL2PB,
  title={IL-2 production by intestinal lamina propria cells in normal inflamed and cancer-bearing colons.},
  author={W. E. Pullman and William F. Doe},
  journal={Clinical and experimental immunology},
  year={1992},
  volume={88 1},
  pages={132-7}
}
Biologically significant levels of IL-2 activity were produced by isolated lamina propria mononuclear cells (LPMC) from normal intestine (n = 12), cancer-bearing colons (n = 35) and inflammatory bowel disease (IBD) affected tissue (n = 12). The levels of IL-2 produced were similar for all three sources of LPMC (normal 252 +/- 48 U/ml, IBD-affected mucosa 197 +/- 42 U/ml and colon cancer 285 +/- 43 U/ml). These levels were significantly greater than those produced by peripheral blood mononuclear… CONTINUE READING