IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.

@article{Krulov1997IL2inducedPR,
  title={IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.},
  author={Magdal{\'e}na Krulov{\'a} and Helona Havelkov{\'a} and Marcela Kosařov{\'a} and Vladimir Holan and Augustinus A. M. Hart and Peter D{\'e}mant and Marie Lipoldov{\'a}},
  journal={Genomics},
  year={1997},
  volume={42 1},
  pages={11-5}
}
Lymphocytes of mouse strains BALB/cHeA (BALB/c) and STS/A (STS) differ in the IL-2-induced proliferative response, STS being a high and BALB/c a low responder in the range of concentrations 125-2000 IE/ml. We analyzed the genetic basis of this strain difference using the recombinant congenic (RC) strains of the BALB/c-c-STS/Dem (CcS/Dem) series. This series comprises 20 homozygous strains all derived from two parental inbred strains: the "background" strain BALB/c and the "donor" strain STS… CONTINUE READING