IL-2 and IL-10 production by human CD4+T cells is differentially regulated by p38: mode of stimulation-dependent regulation of IL-2.

@article{Veiopoulou2004IL2AI,
  title={IL-2 and IL-10 production by human CD4+T cells is differentially regulated by p38: mode of stimulation-dependent regulation of IL-2.},
  author={Christina Veiopoulou and Olga Kogopoulou and Evaggelos Tzakos and George Mavrothalassitis and Dimitris I Mitsias and Anastasia S Karafoulidou and Fotini Paliogianni and H M Moutsopoulos and George Thyphronitis},
  journal={Neuroimmunomodulation},
  year={2004},
  volume={11 4},
  pages={199-208}
}
Antigenic stimulation of T cells initiates a complex series of intracellular signaling pathways that target and activate different cytokine genes. The participation of mitogen-activated protein kinases (MAPKs) in these processes has not been studied thoroughly and in some instances conflicting results have been reported. Here we have examined the role of p38 MAPK on IL-2 and IL-10 production following activation of human CD4+ T cells or of the leukemic cell line Hut-78, with either plate-bound… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…