IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp.

@article{Pan2001IL1HAI,
  title={IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp.},
  author={Guangjin Pan and Philip Risser and Wen-ge Mao and Daryl Baldwin and Aihong Zhong and Ellen Filvaroff and Daniel G. Yansura and Lindsay B. Lewis and Charles Eigenbrot and William J. Henzel and Richard Vandlen},
  journal={Cytokine},
  year={2001},
  volume={13 1},
  pages={
          1-7
        }
}
IL-18, or IGIF (interferon-gamma inducing factor), is an IL-1-related, pro-inflammatory cytokine, which plays a pivotal role in systemic and local inflammation. We have identified and characterized IL-1H, a novel IL-1-related molecule. IL-1H appears to be expressed in most tissues with relatively high levels in testis, thymus and uterus. The IL-1H transcripts were stimulated by phorbol ester (PMA) in human cell lines (A431, THP-1 and KG-1) and peripheral blood mononuclear cells (HPBMC) and… CONTINUE READING
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