IL-18 polymorphisms in hepatitis B virus related liver disease.

@article{Karra2015IL18PI,
  title={IL-18 polymorphisms in hepatitis B virus related liver disease.},
  author={Vijay Kumar Karra and Phani Kumar Gumma and Soumya Jyoti Chowdhury and Rajesh Ruttala and Sunil Kumar Polipalli and Anita Chakravarti and Premashis Kar},
  journal={Cytokine},
  year={2015},
  volume={73 2},
  pages={277-82}
}
Interleukine-18 (IL-18) was originally called interferon (INF-γ) inducing factor and plays a critical dual role in Th1 polarization and viral clearance. We aimed to explore whether single-nucleotide promoter polymorphisms (SNPs) are associated with the outcome of hepatitis B virus (HBV) infection. 271 HBV infected patients were recruited in this study out of these 109 were spontaneously recovered and 162 were diagnosed to be having persistent HBV infection which includes 48 chronic hepatitis… CONTINUE READING
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