IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation.

@article{Hall2010IL18AU,
  title={IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation.},
  author={Isaac E Hall and Sri Yarlagadda and Steven G Coca and Zhu Wang and Mona Doshi and Prasad Devarajan and Won Kyo Han and Richard J. Marcus and Chirag R Parikh},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2010},
  volume={21 1},
  pages={
          189-97
        }
}
Current methods for predicting graft recovery after kidney transplantation are not reliable. We performed a prospective, multicenter, observational cohort study of deceased-donor kidney transplant patients to evaluate urinary neutrophil gelatinase-associated lipocalin (NGAL), IL-18, and kidney injury molecule-1 (KIM-1) as biomarkers for predicting dialysis within 1 wk of transplant and subsequent graft recovery. We collected serial urine samples for 3 d after transplant and analyzed levels of… CONTINUE READING

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