IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes.

@article{Joseph2012IL17SD,
  title={IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes.},
  author={Julie Joseph and Stefan Bittner and Fabian M. P. Kaiser and Heinz Wiendl and Stephan Kissler},
  journal={Journal of immunology},
  year={2012},
  volume={188 1},
  pages={216-21}
}
The long-held view that many autoimmune disorders are primarily driven by a Th1 response has been challenged by the discovery of Th17 cells. Since the identification of this distinct T cell subset, Th17 cells have been implicated in the pathogenesis of several autoimmune diseases, including multiple sclerosis and rheumatoid arthritis. Type 1 diabetes has also long been considered a Th1-dependent disease. In light of the emerging role for Th17 cells in autoimmunity, several recent studies… CONTINUE READING
28 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…