IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects

@inproceedings{RamirezVelazquez2013IL17producingPB,
  title={IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects},
  author={Carlos Ramirez-Velazquez and Elena C Castillo and Leopoldo Ricardo Guido-Bayardo and Vianney Ortiz-Navarrete},
  booktitle={Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology},
  year={2013}
}
BACKGROUND A T helper cell (TH) 17-biased response has been observed in patients with allergic asthma, particularly in those with neutrophil accumulation in the lung. Therefore, we sought to test the hypothesis that neutrophils might be an important source of interleukin (IL)-17 in allergic asthma. METHODS Whole peripheral blood cells from non-asthmatic control subjects (n = 17) and patients with mild asthma (n = 7), moderate but persistent asthma (n = 4), or acute asthma (n = 6) were… CONTINUE READING
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