IL-17-producing T cells in lung immunity and inflammation.

  title={IL-17-producing T cells in lung immunity and inflammation.},
  author={Chiara Nembrini and Benjamin J Marsland and Manfred Kopf},
  journal={The Journal of allergy and clinical immunology},
  volume={123 5},
  pages={986-94; quiz 995-6}
T(H)17 cells are a recently described effector CD4 T-cell subset characterized by the production of IL-17A, IL-17F, and IL-22, which have been implicated in the pathogenesis of several autoimmune diseases. T(H)17 and other IL-17A-producing T cells, including a population of gammadelta T cells and natural killer T cells, have also been associated with the development of skin, intestinal, and lung inflammatory diseases, such as asthma, granulomatous disease, chronic obstructive pulmonary disease… CONTINUE READING


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