IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.

@article{Cho2010IL17IE,
  title={IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.},
  author={John S. Cho and Eric M Pietras and N. Castrillo Garcia and Romela Irene Ramos and David M Farzam and Holly R Monroe and Julie E. Magorien and Andrew Blauvelt and Jay K. Kolls and Ambrose L Cheung and Genhong Cheng and Robert L. Modlin and Lloyd S. Miller},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 5},
  pages={
          1762-73
        }
}
Staphylococcus aureus is the most common cause of skin and soft tissue infections, and rapidly emerging antibiotic-resistant strains are creating a serious public health concern. If immune-based therapies are to be an alternative to antibiotics, greater understanding is needed of the protective immune response against S. aureus infection in the skin. Although neutrophil recruitment is required for immunity against S. aureus, a role for T cells has been suggested. Here, we used a mouse model of… Expand
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