IL-13 suppresses double-stranded RNA-induced IFN-λ production in lung cells.

Abstract

Acute asthma exacerbations are frequently associated with respiratory viral infections. Although impaired production of type III IFNs (IFN-λs) is related to the severity of asthma exacerbation, the mechanisms underlying deficient IFN-λ production in asthma are poorly understood. Airway epithelial cells were stimulated in vitro with a synthetic mimetic of… (More)
DOI: 10.1016/j.bbrc.2010.12.082

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