IL-13 receptor α2 stimulates human glioma cell growth and metastasis through the Src/PI3K/Akt/mTOR signaling pathway

@article{Tu2016IL13R,
  title={IL-13 receptor $\alpha$2 stimulates human glioma cell growth and metastasis through the Src/PI3K/Akt/mTOR signaling pathway},
  author={Ming-chi Tu and Wei Wange and Lin Cai and Penglei Zhu and Zhichao Gao and Wei-ming Zheng},
  journal={Tumor Biology},
  year={2016},
  volume={37},
  pages={14701-14709}
}
Glioma is a malignant tumor that affects all kinds of people all over the world. It demonstrates remarkable infiltrative and invasive features. The high expression of interleukin-13 receptor subunit alpha-2 (IL-13Rα2) reportedly plays a pivotal role in some cancers. However, whether IL-13Rα2 contributes to glioma remains unknown. This study demonstrates that IL-13Rα2 is significantly up-regulated in human glioma tissue samples. It is also associated with late stages of disease progression and… 
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