IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent.

@article{Tekkanat2001IL13inducedAH,
  title={IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent.},
  author={Kim K. Tekkanat and Hunein F. Maassab and Daniel S. Cho and Joyce J. Lai and A Elefteriades John and Aaron A. Berlin and Mark H Kaplan and Nicholas W Lukacs},
  journal={Journal of immunology},
  year={2001},
  volume={166 5},
  pages={
          3542-8
        }
}
Airway damage and hyperreactivity induced during respiratory syncytial virus (RSV) infection can have a prolonged effect in infants and young children. These infections can alter the long-term function of the lung and may lead to severe asthma-like responses. In these studies, the role of IL-13 in inducing and maintaining a prolonged airway hyperreactivity response was examined using a mouse model of primary RSV infection. Using this model, there was evidence of significant airway epithelial… CONTINUE READING

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