IL-12 Production Induced by Agaricus blazei Fraction H (ABH) Involves Toll-like Receptor (TLR)

@article{Kasai2004IL12PI,
  title={IL-12 Production Induced by Agaricus blazei Fraction H (ABH) Involves Toll-like Receptor (TLR)},
  author={Hirotake Kasai and Lu Mei He and Masaki Kawamura and Peitzu T. Yang and Xing Wang Deng and Mwansa Munkanta and Arisa Yamashita and Hiroshi Terunuma and Michihiro Hirama and Isao Horiuchi and Takeshi Natori and Teiichiro Koga and Yasuko Amano and Nobuo Yamaguchi and Morihiro Ito},
  journal={Evidence-based Complementary and Alternative Medicine},
  year={2004},
  volume={1},
  pages={259 - 267}
}
Agaricus blazei Murill is an edible fungus used in traditional medicine, which has various well-documented medicinal properties. In the present study, we investigated the effects of hemicellulase-derived mycelia extract (Agaricus blazei fraction H: ABH) on the immune system. First, we examined the cytokine-inducing activity of ABH on human peripheral mononuclear cells (PBMC). The results indicated that ABH induced expression of IL-12, a cytokine known to be a critical regulator of cellular… CONTINUE READING
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