• Published 2008

IL-12联合结核杆菌DNA疫苗初免-BCG加强免疫的免疫效果观察

@inproceedings{2008IL12DNABCG,
  title={IL-12联合结核杆菌DNA疫苗初免-BCG加强免疫的免疫效果观察},
  author={高蕾 and 鲍朗 and 郝牧 and 章乐 and 秦紫芳},
  year={2008}
}
Objective To investigate the immunogenicity of vaccine strategies about human interleukin 12 associated with combined DNA (Ag85A and ESAT-6) prime-BCG boost. Methods BALB/c mice were divided into PBS negative control and 4 immunity groups: BCG group, DNA/BCG group, DNA+IL-12/BCG group and DNA/BCG+IL-12 group. All mice received three immunizations at 2-week interval. Specific IgG antibody in serum of mice was determined with indirect ELISA in 4, 6, 8 weeks respectively after final vaccination… CONTINUE READING