IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy

Abstract

The minor haplotype −3575A/-2849G/-2763C in IL-10 promoter has been defined as a marker of disease resistance to leprosy and its severity in Brazilian population. Our investigation of six single-nucleotide polymorphisms (SNPs) in IL-10 promoter in 282 Indian leprosy patients and 266 healthy controls by direct PCR sequencing, however, showed that the… (More)
DOI: 10.1007/s00439-005-0042-8

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