Corpus ID: 1258992

IL-10-producing type 1 regulatory T cells and allergy.

@article{Wu2007IL10producingT1,
  title={IL-10-producing type 1 regulatory T cells and allergy.},
  author={K. Wu and Yutian Bi and K. Sun and Changzheng Wang},
  journal={Cellular & molecular immunology},
  year={2007},
  volume={4 4},
  pages={
          269-75
        }
}
As an important subset of regulatory T (Treg) cells, IL-10-producing type 1 regulatory T cells (Tr1), have some different features to thymic-derived naturally occurring CD4+CD25+Foxp3+ Treg cells(nTreg cells). Similar to nTreg cells, Tr1 also play important roles in the control of allergic inflammation in several ways. There is a fine balance between Tr1 and Th2 responses in healthy subjects. Skewing of allergic-specific effector T cells to a Tr1 phenotype appears to be a critical event in… Expand
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