IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy.

@article{Jutel2003IL10AT,
  title={IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy.},
  author={Marek Jutel and M{\"u}beccel Akdis and Ferah Budak and Carmen Aebischer-Casaulta and Maria Wrzyszcz and Kurt Blaser and Cezmi A. Akdis},
  journal={European journal of immunology},
  year={2003},
  volume={33 5},
  pages={1205-14}
}
The regulation of normal and allergic immune responses to airborne allergens in the mucosa is still poorly understood, and the mechanism of specific immunotherapy (SIT) in normalizing the allergic response to such allergens is currently not clear. Accordingly, we have investigated the immunoregulatory mechanism of both normal and allergic responses to the major house-dust mite (HDM) and birch pollen allergens--Dermatophagoides pteroynyssinus (Der p)1 and Bet v 1, respectively--as well as the… CONTINUE READING
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