IL 1-like activity in antigen-presenting human B cell lines.

@article{Gerrard1985IL1A,
  title={IL 1-like activity in antigen-presenting human B cell lines.},
  author={Thomas J. Gerrard and David J Volkman},
  journal={Journal of immunology},
  year={1985},
  volume={135 5},
  pages={
          3217-23
        }
}
The secretion of interleukin 1 (IL 1) by an antigen-presenting cell (APC) may be essential to its function in the stimulation of T cell responses. However, the relevance of IL 1 is less clear in cases where the APC are from continuous B cell lines. We have shown that IL 1-like activity can be demonstrated in human B cell lines by using a cellular co-culture assay for IL 1. Significant IL 1 activity could not be detected in the supernatants of these B cell lines produced either constitutively or… CONTINUE READING