IIS – Integrated Interactome System: A Web-Based Platform for the Annotation, Analysis and Visualization of Protein-Metabolite-Gene-Drug Interactions by Integrating a Variety of Data Sources and Tools

@inproceedings{Carazzolle2014IISI,
  title={IIS – Integrated Interactome System: A Web-Based Platform for the Annotation, Analysis and Visualization of Protein-Metabolite-Gene-Drug Interactions by Integrating a Variety of Data Sources and Tools},
  author={Marcelo Falsarella Carazzolle and Lucas Miguel de Carvalho and Hugo Henrique Slepicka and Ramon Vidal and Gonçalo Amarante Guimar{\~a}es Pereira and J{\"o}rg Kobarg and Gabriela Vaz Meirelles},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND High-throughput screening of physical, genetic and chemical-genetic interactions brings important perspectives in the Systems Biology field, as the analysis of these interactions provides new insights into protein/gene function, cellular metabolic variations and the validation of therapeutic targets and drug design. However, such analysis depends on a pipeline connecting different tools that can automatically integrate data from diverse sources and result in a more comprehensive… CONTINUE READING
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