IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting.

Abstract

Solitary fibrous tumour (SFT) is a mesenchymal neoplasm composed of CD34-positive fibroblastic cells. The pathogenesis driving this neoplasm remains unclear, with no recurrent genetic aberrations described to date. Previous reports suggest a role for IGF2 over-expression in the pathogenesis of these tumours, implicated in triggering hypoglycaemia in some… (More)
DOI: 10.1002/path.2715

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Cite this paper

@article{Hajdu2010IGF2OI, title={IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting.}, author={Mihai Hajdu and Samuel Singer and Robert G. Maki and Gary K. Schwartz and Mary Lou Keohan and Cristina R Antonescu}, journal={The Journal of pathology}, year={2010}, volume={221 3}, pages={300-7} }