IGF1 mRNA isoform expression in the cervix of HPV-positive women with pre-cancerous and cancer lesions.

@article{Koczorowska2011IGF1MI,
  title={IGF1 mRNA isoform expression in the cervix of HPV-positive women with pre-cancerous and cancer lesions.},
  author={Maria Magdalena Koczorowska and Anna Kwaśniewska and Anna Goździcka-J{\'o}zefiak},
  journal={Experimental and therapeutic medicine},
  year={2011},
  volume={2 1},
  pages={
          149-156
        }
}
Human papillomavirus (HPV) plays a crucial role in cervical cancer etiology. However, not all HPV-infected women develop cancer, indicating that additional cellular factors facilitate carcinogenesis. The aim of this study was to analyze the expression profile of insulin-like growth factor 1 (IGF1) isoforms in the context of FOX2, SP1 and IGF1 receptor (IGF1R) expression during HPV-dependent cervical carcinogenesis. One hundred and nine epithelial tissue samples from women with pre-cancerous and… CONTINUE READING
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