IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.

  title={IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.},
  author={Li Xu and Rui Zhou and Lezhong Yuan and Shiqing Wang and Xiaoyin Li and Huanrong Ma and Minyu Zhou and Changqie Pan and Jingwen Zhang and Na Ling Huang and Min Shi and Jianping Bin and Yulin Liao and Wangjun Liao},
  journal={Cancer letters},
Interferon-induced transmembrane proteins (IFITMs) are expressed in some types of cancer. However, their precise roles in tumor progression remain unclear. The present study investigated the function of IFITM2 in gastric cancer (GC) progression. A retrospective analysis of a public database and 167 GC patients revealed that IFITM2 expression was upregulated in gastric tumor samples, which was positively correlated with disease progression, more frequent postoperative recurrence, and higher… CONTINUE READING
Highly Cited
This paper has 461 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-8 of 8 extracted citations

Effects of sucrose ester structures on liposome-mediated gene delivery.

Acta biomaterialia • 2018
View 6 Excerpts
Highly Influenced

461 Citations

Citations per Year
Semantic Scholar estimates that this publication has 461 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 30 references

Global cancer statistics.

CA: a cancer journal for clinicians • 2011
View 4 Excerpts
Highly Influenced

The IFITM proteins inhibit HIV-1 infection.

Journal of virology • 2011
View 5 Excerpts
Highly Influenced

Clinical significance of ac curate identification of lymph node status in dista nt metastatic gastric cancer

R Zhou
Oncotarget, 2016 • 2016
View 1 Excerpt

MACC1 mediates acetylcholin e-i duced invasion and migration by human gastric c ancer cells

T Yang
Oncotarget, 2016 • 2016
View 1 Excerpt

Novel STAT 3 inhibitors for treating gastric cancer.

Expert opinion on investigational drugs • 2016
View 1 Excerpt

The involvement of survivin insulin-like growth factor 1-induced epithelial-m esenchymal transition in gastric cancer

C Li
Tumour Biol, • 2016
View 1 Excerpt

Similar Papers

Loading similar papers…