IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition

@article{Morali2001IGFIIIR,
  title={IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition},
  author={Olivier G Morali and V{\'e}ronique Delmas and Robert Moore and Christine Jeanney and Jean Paul Thiery and Lionel Larue},
  journal={Oncogene},
  year={2001},
  volume={20},
  pages={4942-4950}
}
The epithelium to mesenchyme transition is thought to play a fundamental role during embryonic development and tumor progression. Loss of cell–cell adhesion and modification of both cell morphology and gene expression are the main events associated with this transition. There is a large amount of evidence suggesting that growth factors can initiate these events. Yet, the connection from growth factor induction to changes in cell adhesion and morphology is largely unknown. To elucidate this… CONTINUE READING
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