IGF-II expression and methylation in small for gestational age infants.

@article{Zhang2015IGFIIEA,
  title={IGF-II expression and methylation in small for gestational age infants.},
  author={Shulian Zhang and Guanpeng Zhai and Jin Wang and Wenjing Shi and Rong Zhang and Chao Chen},
  journal={Journal of pediatric endocrinology & metabolism : JPEM},
  year={2015},
  volume={28 5-6},
  pages={613-8}
}
BACKGROUND Low birth weight is associated with an increased risk of adverse outcomes in many diseases in adult life. We investigated the expression of IGF-II and the status of differentially methylated regions (DMR) in small for gestational age (SGA) infants after birth. METHODS Plasma IGF-II, IGF-II receptor (IGF2R), IGF-I, and IGF-binding protein 3 (IGFBP3) levels were measured after birth in 150 newborn infants. These included 30 term appropriate for gestational age (AGA), 30 term SGA, 30… CONTINUE READING