IGF-IEc expression, regulation and biological function in different tissues.

@article{Dai2010IGFIEcER,
  title={IGF-IEc expression, regulation and biological function in different tissues.},
  author={Zhong-quan Dai and Feng Wu and Ella W. Yeung and Yinghui Li},
  journal={Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society},
  year={2010},
  volume={20 4},
  pages={275-81}
}
Insulin-like growth factor I (IGF-I) is an important growth factor for embryonic development, postnatal growth, tissue repair and maintenance of homeostasis. IGF-I functions and regulations are complex and tissue-specific. IGF-I mediates growth hormone signaling to target tissues during growth, but many IGF-I variants have been discovered, resulting in complex models to describe IGF-I function and regulation. Mechano-growth factor (MGF) is an alternative splicing variant of IGF-I and serves as… CONTINUE READING