IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.

@article{DAloisio2009IGFIAI,
  title={IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.},
  author={Aimee A D'Aloisio and Jane C. Schroeder and Kari E. North and C. Poole and Suzanne L. West and Gregory S. Travlos and Donna D. Baird},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2009},
  volume={18 3},
  pages={954-66}
}
Circulating insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) levels have been associated with common diseases. Although family-based studies suggest that genetic variation contributes to circulating IGF-I and IGFBP-3 levels, analyses of associations with multiple IGF-I and IGFBP-3 single nucleotide polymorphisms (SNP) have been limited, especially among African Americans. We evaluated 30 IGF-I and 15 IGFBP-3 SNPs and estimated diplotypes in association with plasma IGF-I… CONTINUE READING