IGF-I, growth hormone, and/or exercise effects on non-weight-bearing soleus of hypophysectomized rats.

@article{Roy1996IGFIGH,
  title={IGF-I, growth hormone, and/or exercise effects on non-weight-bearing soleus of hypophysectomized rats.},
  author={Roland R. Roy and Cao Phạm Tr{\'i} and Elena J Grossman and Robert J Talmadge and Richard E. Grindeland and Venkat R. Mukku and V. Reggie Edgerton},
  journal={Journal of applied physiology},
  year={1996},
  volume={81 1},
  pages={
          302-11
        }
}
The effects of insulin-like growth factor (IGF-I) or growth hormone (GH) with and without exercise on predominantly slow muscles of hypophysectomized hindlimb-suspended (HS) rats were determined. HS resulted in a 21, 23, and 30% decrease in soleus, adductor longus, and vastus intermedius masses, respectively, compared with ambulatory rats. Compared with values in HS rats, IGF-I increased the vastus intermedius mass and GH or exercise alone increased both the soleus and vastus intermedius masses… CONTINUE READING

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