IGF-1 Regulates Cyr61 Induced Breast Cancer Cell Proliferation and Invasion

@inproceedings{Sarkissyan2014IGF1RC,
  title={IGF-1 Regulates Cyr61 Induced Breast Cancer Cell Proliferation and Invasion},
  author={Suren Sarkissyan and Marianna Sarkissyan and Yanyuan Wu and Jessica Cardenas and H Phillip Koeffler and Jaydutt V Vadgama},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Studies from our laboratory and others have shown that cysteine-rich 61 (Cyr61) may be involved in tumor proliferation and invasion. In earlier studies, we demonstrated increased insulin-like growth factor-I (IGF-1) is associated with breast tumor formation and poor clinical outcomes. In our current study we have investigated IGF-1 regulation of… CONTINUE READING