IGF, type I IGF receptor and IGF-binding protein mRNA expression in the developing mouse lung.

@article{Schuller1995IGFTI,
  title={IGF, type I IGF receptor and IGF-binding protein mRNA expression in the developing mouse lung.},
  author={Alwin G.P. Schuller and Johan Wilhelm Van Neck and Remko Beukenholdt and Ellen C. Zwarthoff and Stenvert L. S. Drop},
  journal={Journal of molecular endocrinology},
  year={1995},
  volume={14 3},
  pages={349-55}
}
The IGFs are important mitogens involved in lung growth and development. The regulation of IGF action depends not only on the expression of IGFs and IGF receptors, but also on the modulation of IGF activity by IGF-binding proteins (IGFBPs). In this study, we describe the mRNA expression of IGF-I, IGF-II, type I IGF receptor, IGFBP-2, IGFBP-4 and IGFBP-5 during mouse lung development as studied by in situ hybridization techniques. The IGF, type I IGF receptor and IGFBP-2, -4 and -5 genes were… CONTINUE READING
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