IFN-gamma-inducible chemokines enhance adaptive immunity and colitis.

Abstract

T helper type 1 (Th1) cells secreting interferon-gamma (IFN-gamma) have been closely associated with Crohn's disease (CD). Monokine-induced by IFN-gamma (MIG), IFN-gamma-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10), are chemokines that bind CXCR3 and mediate the chemotaxis of leukocytes. IP-10, MIG, and CXCR3… (More)

Topics

Cite this paper

@article{Singh2003IFNgammainducibleCE, title={IFN-gamma-inducible chemokines enhance adaptive immunity and colitis.}, author={Udai Pratap Singh and Shailesh Singh and Nuzhat Iqbal and Casey T. Weaver and Jerry R. Mcghee and James W. Lillard}, journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research}, year={2003}, volume={23 10}, pages={591-600} }