IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774.

Abstract

Interleukin (IL)-12 is a logical candidate for participation in the differentiation of T helper (Th) 1 cells. IL-12 is produced by macrophages and B cells and induces the production of interferon (IFN)-gamma from Th1 cells and NK cells. In this study, we show that the IFN-gamma itself is capable of inducing IL-12 mRNA expression in murine macrophage cell… (More)

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@article{Yoshida1994IFNgammaII, title={IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774.}, author={Atsushi Yoshida and Yuichi Koide and Masato Uchijima and Takato O. Yoshida}, journal={Biochemical and biophysical research communications}, year={1994}, volume={198 3}, pages={857-61} }