IFN-alpha in vivo enhances tumor necrosis factor receptor levels on hairy cells.

@article{Billard1990IFNalphaIV,
  title={IFN-alpha in vivo enhances tumor necrosis factor receptor levels on hairy cells.},
  author={Christian Billard and François Sigaux and Juana Wietzerbin},
  journal={Journal of immunology},
  year={1990},
  volume={145 6},
  pages={1713-8}
}
Hairy cell leukemia (HCL) is a preplasma B cell neoplasia that is characterized by monocytopenia and responds to IFN-alpha therapy. We investigated the expression of receptors for TNF-alpha, a monocyte-derived cytokine, on the surface of hairy cells from seven HCL patients before and after treating them with IFN-alpha. Iodinated TNF-alpha binding… CONTINUE READING