IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus.

@article{Rose2013IFNAI,
  title={IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus.},
  author={Thomas Rose and Andreas Gr{\"u}tzkau and Heike Hirseland and D{\"o}rte Huscher and Cornelia Daehnrich and Andrzej Dzionek and Tobias Ozimkowski and Wolfgang Schlumberger and Philipp Enghard and Andreas Radbruch and Gabriela Riemekasten and G J Burmester and Falk Hiepe and Robert Biesen},
  journal={Annals of the rheumatic diseases},
  year={2013},
  volume={72 10},
  pages={1639-45}
}
OBJECTIVES To evaluate and compare the clinical efficacy of three biomarkers for interferon (IFN) activity (measured directly and indirectly) and six traditional biomarkers in indicating current and prospective disease activity (DA) in systemic lupus erythematosus (SLE). METHODS IFNα (dissociation-enhanced lanthanide fluorescent immunoassay), IFNγ-inducible protein 10 (IP-10) (ELISA) and sialic acid-binding Ig-like lectin 1 (SIGLEC-1) (flow cytometry) were measured in 79 accurately… CONTINUE READING
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IFN α and its response proteins , IP - 10 and SIGLEC - 1 , are biomarkers of disease activity in systemic lupus erythematosus , Annals of the rheumatic diseases

T. Rose, A. Grützkau, +6 authors P. Enghard
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