IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in the Belgian population.

@article{Aminkeng2009IFIH1GP,
  title={IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in the Belgian population.},
  author={Folefac Aminkeng and Jan E van Autreve and Ilse Weets and Erik Quartier and Chris van Schravendijk and Frans K. Gorus and Bart J R Van der Auwera},
  journal={Human immunology},
  year={2009},
  volume={70 9},
  pages={706-10}
}
The evaluation of susceptibility loci in a registry-based setting could be an important addition to the current predictive and screening models in T1D. Therefore, the aim of this study was to evaluate the importance of one of these loci, IFIH1. T1D patients (n=1981), control subjects (n=2092) and 430 families were genotyped for HLA-DQ and IFIH1 nsSNP rs1990760 (Ala946Thr). In the association analysis, the allelic frequencies, A (62.4% vs. 61.3%) and G (37.6% vs. 38.7%) were similar in cases and… CONTINUE READING

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IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk

European Journal of Human Genetics • 2008
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Highly Influenced

susceptibility locusmaps to chromosome 21 q 22 . 3

S Liu, H Wang, +3 authors J Pedersen
2008

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