IELs: enforcing law and order in the court of the intestinal epithelium.

@article{Cheroutre2005IELsEL,
  title={IELs: enforcing law and order in the court of the intestinal epithelium.},
  author={Hilde Cheroutre},
  journal={Immunological reviews},
  year={2005},
  volume={206},
  pages={
          114-31
        }
}
The intestinal intraepithelial lymphocytes (IELs) are mostly T cells dispersed as single cells within the epithelial cell layer that surrounds the intestinal lumen. IELs are, therefore, strategically located at the interface between the antigen-rich outside world and the sterile core of the body. The intestine of higher vertebrates has further evolved to harbor numerous commensal bacteria that carry out important functions for the host, and while defensive immunity can effectively protect… CONTINUE READING
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