IDH1 mutation-associated long non-coding RNA expression profile changes in glioma

@article{Zhang2015IDH1ML,
  title={IDH1 mutation-associated long non-coding RNA expression profile changes in glioma},
  author={Xiao-qin Zhang and Karrie Mei-Yee Kiang and Yue-chun Wang and Jenny Kan-Suen Pu and Amy Shuk-Wai Ho and Stephen W. Y. Cheng and D. W. K. Lee and Ping-De Zhang and Jia-Jing Chen and Wai-man Lui and C. F. Fung and Gilberto Ka-Kit Leung},
  journal={Journal of Neuro-Oncology},
  year={2015},
  volume={125},
  pages={253-263}
}
Isocitrate dehydrogenase 1 (IDH1) mutation is an important prognostic marker in glioma. However, its downstream effect remains incompletely understood. Long non-coding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis in a number of human malignancies, including glioma. Here, we investigated whether and how lncRNA expression profiles would differ between gliomas with or without IDH1 mutation. By using our previously reported lncRNA mining approach, we performed lncRNA… CONTINUE READING
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