IDH1 and IDH2 mutations in different histologic subtypes and WHO grading gliomas in a sample from Northern Brazil.

@article{Pessoa2015IDH1AI,
  title={IDH1 and IDH2 mutations in different histologic subtypes and WHO grading gliomas in a sample from Northern Brazil.},
  author={Igor de Ara{\'u}jo Pessoa and Fernanda Espirito-Santo Sagica and Nilson Praia Anselmo and Jos{\'e} Reginaldo Nascimento Brito and Edivaldo Herculano Corr{\^e}a de Oliveira},
  journal={Genetics and molecular research : GMR},
  year={2015},
  volume={14 2},
  pages={6533-42}
}
Glioma is a term used to describe tumors derived from glial cells. These tumors are divided into subgroups based on the histological morphology and similarity of their differentiated glia cells. Traditionally, they are classified according to the World Health Organization and include astrocytomas, oligodendrogliomas, ependymomas, and oligoastrocytomas. Like most cancers, gliomas develop as a result of genetic changes that accumulate with tumor progression. Alterations in isocitrate… CONTINUE READING