IDENTIFICATION AND DETERMINATION OF THE MAJOR CONSTITUENTS IN AN ANTIANGIOGENESIS HERBAL FORMULA, QING-LUO-FANG, BY HPLC—DAD—ESI/MS

@article{Yang2010IDENTIFICATIONAD,
  title={IDENTIFICATION AND DETERMINATION OF THE MAJOR CONSTITUENTS IN AN ANTIANGIOGENESIS HERBAL FORMULA, QING-LUO-FANG, BY HPLC—DAD—ESI/MS},
  author={Shuai Yang and Kai-tong Li and Yi-xuan Zhang and Shao-Hui Li and Yue Shi},
  journal={Journal of Liquid Chromatography \& Related Technologies},
  year={2010},
  volume={33},
  pages={1842 - 1853}
}
A high-performance liquid chromatography—diode array UV detection—electrospray ionization tandem mass spectrometry (HPLC—DAD—ESI-MS) method was established for the simultaneous qualitative and quantitative analysis of the major bioactive constituents in Qing-Luo-Fang (QLF), an anti-angiogenesis herbal formula. The separation was performed on a Phenomenex Gemini C18 column using gradient elution. The mobile phase A was ammonium acetate (10 mM) in water; and mobile phase B was methanol… 
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