ICRF 159-induced cell-cycle perturbation in vitro: its relationship to inhibition of colony-forming ability.

@article{Edgar1981ICRF1C,
  title={ICRF 159-induced cell-cycle perturbation in vitro: its relationship to inhibition of colony-forming ability.},
  author={David H. Edgar and Andrew M. Creighton},
  journal={British Journal of Cancer},
  year={1981},
  volume={44},
  pages={236 - 240}
}
The effects of single doses of ICRF 159 (Razoxane) on the cell-cycle kinetics of lines of BKH 21S cells in vitro were studied by means of flow micro-fluorometry (FMF). A characteristic accumulation of cells in the 4n DNA region after 6 h in the presence of ICRF 159 was evident in cells which were sensitive to the cytotoxic effects of the agents, as judged… CONTINUE READING