ICON: The Early Diagnosis of Congenital Immunodeficiencies

  title={ICON: The Early Diagnosis of Congenital Immunodeficiencies},
  author={John M. Routes and Mario Abinun and Waleed Al-Herz and Jacinta Bustamante and A Condino-neto and Maria Teresa De La Morena and Amos Etzioni and Eleonora Gambineri and Elie Haddad and Lisa J. Kobrynski and Françoise le Deist and Shigeaki Nonoyama and Joao Bosco Oliveira and Elena Ronda P{\'e}rez and Capucine Picard and Nima Attaran Rezaei and John William Sleasman and Kathleen E Sullivan and Troy T Torgerson},
  journal={Journal of Clinical Immunology},
Primary immunodeficiencies are intrinsic defects in the immune system that result in a predisposition to infection and are frequently accompanied by a propensity to autoimmunity and/or immunedysregulation. Primary immunodeficiencies can be divided into innate immunodeficiencies, phagocytic deficiencies, complement deficiencies, disorders of T cells and B cells (combined immunodeficiencies), antibody deficiencies and immunodeficiencies associated with syndromes. Diseases of immune dysregulation… CONTINUE READING
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