ICAM-1 receptors and cold viruses.

@article{Bella2000ICAM1RA,
  title={ICAM-1 receptors and cold viruses.},
  author={Jordi Bella and Michael G. Rossmann},
  journal={Pharmaceutica acta Helvetiae},
  year={2000},
  volume={74 2-3},
  pages={291-7}
}
Human rhinoviruses (HRVs), the single most important etiologic agent of common colds, are small viruses composed of an icosahedral protein shell that encapsidates a single, positive RNA strand. Multiplication of HRVs occurs in the cytoplasm of the host cell. To produce infection, HRVs must first attach to specific cellular receptors embedded in the plasma membrane. Ninety percent of HRVs immunogenic variants use as receptor intercellular adhesion molecule-1 (ICAM-1), a cell surface glycoprotein… CONTINUE READING
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