ICAM-1 in acute myocardial infarction: a potential therapeutic target.

@article{Benson2007ICAM1IA,
  title={ICAM-1 in acute myocardial infarction: a potential therapeutic target.},
  author={Victoria L. Benson and Aisling Clare McMahon and Harry Claude Lowe},
  journal={Current molecular medicine},
  year={2007},
  volume={7 2},
  pages={219-27}
}
Current treatments for AMI centre on prompt restoration of epicardial coronary blood flow. Despite improvements, AMI is still associated with significant morbidity and mortality. Novel approaches are therefore keenly sought. Intercellular adhesion molecule-1 (ICAM-1, CD54) is a member of the immunoglobulin superfamily. It is implicated in neutrophil and monocyte-endothelial cell adhesion, processes contributing to myocardial neutrophil infiltration and microvascular coronary slow flow, both… CONTINUE READING