I1-imidazoline agonist moxonidine decreases sympathetic nerve activity and blood pressure in hypertensives.

@article{Wenzel1998I1imidazolineAM,
  title={I1-imidazoline agonist moxonidine decreases sympathetic nerve activity and blood pressure in hypertensives.},
  author={Ren{\'e} R. Wenzel and Lukas E. Spieker and S G Qui and Sidney Shaw and Thomas Felix L{\"u}scher and Gregor Noll},
  journal={Hypertension},
  year={1998},
  volume={32 6},
  pages={1022-7}
}
Moxonidine is an I1-imidazoline receptor agonist that reduces blood pressure in hypertensives. Experimental data suggest that moxonidine inhibits central sympathetic activity. However, whether such a mechanism is involved in vivo in humans is still unclear. We investigated the effects of 0.4 mg moxonidine orally on muscle sympathetic nerve activity and… CONTINUE READING