I. General Observations concerning the Phenomenon

  title={I. General Observations concerning the Phenomenon},
  author={Lewis Thomas and Robert Alan Good}
Following the description by Shwartzman (1) of the "phenomenon of local tissue reactivity," in 1928, numerous modifications of the original experiment were introduced in order to elicit the phenomenon in organs other than the skin. Various investigators showed that when a suitable bacterial toxin was injected into the substance of tissues, such asp the kidney, lung, intestinal wall, lymph node, joint, conjunctiva, or artery, and followed 24 hours later by an intravenous injection of toxin, the… CONTINUE READING


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