I-region-restricted long-term cultured T cells with helper function for thymic cytotoxic precursor cells.

Abstract

T cells with specific helper function (TM) for the differentiation of thymic cytotoxic T cell precursors (pCTL) into anti-self-TNP effector cells could be enriched in vitro by multiple stimulations with TNP-syngeneic cells after in vivo sensitization with the same hapten. H-2K/D-restricted cytotoxic effector cells (CTL), initially present in such cultures… (More)

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